Chemical Name: BOC-L-Proline
CAS.NO:15761-39-4
Synonyms:Boc-L-Proline
N-(tert-Butyloxycarbonyl)-L-proline
N-(tert-Butoxycarbonyl)-L-proline
(S)-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylic acid
N-Boc-L-proline
Molecular Formula: C10H17NO4
Molecular Weight:215.24600
Physical and Chemical Properties:
Density: 1.201 g / cm3
Boiling point: 337.2ºC at 760 mmHg
Melting point: 133-136ºC
Flash point: 157.7ºC
Refractive index: 1.503
Specification:
Appearance:White to off-white crystalline powder
Purity:≥99.0%
Specification:A white to off-white crystalline powder
Identification by HPLC:The retention time of major peak in the chromatogram of the sample solution corresponds to that in the chromatogram of the standard solution, as obtained in the purity.
Melting range:Between 132 and 137ºC
Water by K.F.:Not more than 0.5% w/w
Chromatographic purity (%area normalization, by HPLC)
1)Purity
2)Total impurities
:Not less than 99.0% Not more than 1.0%
Packing:
25kg / drum
Storage:Closed, cool and dry place below 0ºC.
Application: It can be used to synthesize Daclatasvir which inhibits the HCV protein NS5A, and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).intermediates of Daclatasvir CAS:1009119-64-5
| Items of Analysis | Standard of Analysis | Test Results |
| Appearance | White to off-white powder | White powder |
| Specific rotation | -58.00° ~ -63.00° | -59.21° |
| Water | ≤0.50% | 0.01% |
| Residue on ignition | ≤0.50% | 0.24% |
| Assay | 98.00%～102.00% | 99.40% |
| Purity | ≥99.00% | 99.45% |
| Any major unknown impurity | ≤0.50% | 0.37% |
| Total impurities | ≤1.00% | 0.55% |
| Boc-D-proline | ≤0.05% | 0.04% |
| Conclusion | Conforms to Factory Standard | |
UNICHEMIST manufacture & supply BOC-L-Proline CAS:15761-39-4,if you want to buy it,please drop your inquiry to [email protected] ,we will reply you asap.If you have any custom synthesis or contract manufacturing compounds, please also feel free to contact us.
Factory in Henan Province
The Henan factory is located in the south of Tengda Road and the west of Gongye 3rd Road, Huaiyang District, Zhoukou City, Henan Province. The first phase covers an area of about 200 acres with a total construction area of about 170,496 square meters. It is mainly engaged in the production and sales of pharmaceutical and biological products. More than 800 acres are planned for the second phase. The company has established a stable production service system that can meet the requirements of different quality assurance systems and process conditions, and can realize small-scale process transfer, pilot scale-up, and industrialization, as well as corresponding document registration and auditing.
Factory in Shanxi Province
At the end of 2017, We invested workshop in Xinjiang County Longzhou Chemical Co., Ltd., Xinjiang County Coal Mine Park, Yuncheng, Shanxi. The first phase of the reactors were 30* 2000L~5000L, The contract output value is 50 million annually, factory has passed the audit from public listed company domestic and abroad.
Factory in Shandong Province
The Shandong production plant is located in Liaocheng City, Shandong Province. It has a production workshop covering an area of 2600m², a supporting material warehouse of 800m², a QC laboratory of 150m², and a number of 500~5000L reactors. It has successfully carried out a number of scale-up production projects. The annual output of the body is more than 200 tons.
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